Name: 
 

Chapter 12 Review



Modified True/False
Indicate whether the sentence or statement is true or false.  If false, change the identified word or phrase to make the sentence or statement true.
 

1. 

The replication of a DNA molecule results in four copies of the same gene. _________________________

 

2. 

If a nucleic acid contains uracil, it is DNA. _________________________

 

3. 

The nitrogenous bases in RNA are able to form hydrogen bonds with each other. _________________________

 

4. 

During DNA replication, only one strand of DNA serves as a template. _________________________

 

5. 

Genes determine a person’s eye color by coding for nitrogenous bases that affect eye color. _________________________

 

6. 

DNA codes for DNA polymerase. _________________________

 

7. 

In prokaryotes, an operon is a group of genes that are operated together. _________________________

 

8. 

Gene regulation in eukaryotes is less complex than in prokaryotes. _________________________

 

9. 

The TATA box in eukaryotes helps to ensure transcription. _________________________

 

10. 

In fruit flies, the hox gene that controls the development of the wings is located before the hox gene that controls the development of the eye and before the hox gene that controls the development of the tail. _________________________

 

Multiple Choice
Identify the letter of the choice that best completes the statement or answers the question.
 

11. 

Avery’s experiments showed that bacteria are transformed by
a.
RNA.
b.
DNA.
c.
proteins.
d.
carbohydrates.
 

12. 

What did Griffith observe when he injected a mixture of heat-killed, disease-causing bacteria and live harmless bacteria into mice?
a.
The disease-causing bacteria changed into harmless bacteria.
b.
The mice developed pneumonia.
c.
The harmless bacteria died.
d.
The mice were unaffected.
 

13. 

What would Hershey and Chase have concluded if both radioactive 32P and 35S were found in the bacteria in their experiment?
a.
The virus’s protein coat was not injected into the bacteria.
b.
The virus’s DNA was not injected into the bacteria.
c.
Genes are made of protein.
d.
Both the virus’s protein coat and its DNA were injected into the bacteria.
 

14. 

Which of the following is a nucleotide found in DNA?
a.
ribose + phosphate group + thymine
b.
ribose + phosphate group + uracil
c.
deoxyribose + phosphate group + uracil
d.
deoxyribose + phosphate group + cytosine
 

15. 

Because of base pairing in DNA, the percentage of
a.
adenine molecules in DNA is about equal to the percentage of guanine molecules.
b.
pyrimidines in DNA is about equal to the percentage of purines.
c.
purines in DNA is much greater than the percentage of pyrimidines.
d.
cytosine molecules in DNA is much greater than the percentage of guanine molecules.
 

16. 

DNA is copied during a process called
a.
replication.
b.
translation.
c.
transcription.
d.
transformation.
 

17. 

During DNA replication, a DNA strand that has the bases CTAGGT produces a strand with the bases
a.
TCGAAC.
b.
GATCCA.
c.
AGCTTG.
d.
GAUCCA.
 

18. 

In eukaryotes, DNA
a.
is located in the nucleus.
b.
floats freely in the cytoplasm.
c.
is located in the ribosomes.
d.
is circular.
 

19. 

During mitosis, the
a.
DNA molecules unwind.
b.
histones and DNA molecules separate.
c.
DNA molecules become more tightly coiled.
d.
nucleosomes become less tightly packed.
 

20. 

RNA contains the sugar
a.
ribose.
b.
deoxyribose.
c.
glucose.
d.
lactose.
 

21. 

Unlike DNA, RNA contains
a.
adenine.
b.
uracil.
c.
phosphate groups.
d.
thymine.
 

22. 

Which of the following are found in both DNA and RNA?
a.
ribose, phosphate groups, and adenine
b.
deoxyribose, phosphate groups, and guanine
c.
phosphate groups, guanine, and cytosine
d.
phosphate groups, guanine, and thymine
 

23. 

How many main types of RNA are there?
a.
1
b.
3
c.
hundreds
d.
thousands
 

24. 

Which of the following are copied from DNA?
a.
mRNA only
b.
mRNA, tRNA, and rRNA
c.
mRNA and tRNA only
d.
proteins
 

25. 

What is produced during transcription?
a.
RNA molecules
b.
DNA molecules
c.
RNA polymerase
d.
proteins
 

26. 

During transcription, an RNA molecule is formed
a.
that is complementary to both strands of DNA.
b.
that is identical to part of a single strand of DNA.
c.
that is double-stranded.
d.
inside the nucleus.
 

27. 

Which of the following statements is true?
a.
A promoter is part of an intron.
b.
A pre-mRNA molecule is longer than the gene from which the molecule was transcribed.
c.
Introns have complementary sequences in DNA.
d.
mRNA molecules made from the same gene are always edited the same way.
 

28. 

How many codons are needed to specify three amino acids?
a.
3
b.
6
c.
9
d.
12
 

29. 

Why is it possible for an amino acid to be specified by more than one kind of codon?
a.
Some codons have the same sequence of nucleotides.
b.
There are 64 different kinds of codons but only 20 amino acids.
c.
Some codons do not specify an amino acid.
d.
The codon AUG codes for the amino acid methionine and serves as the “start” codon for protein synthesis.
 

30. 

Which of the following terms is LEAST closely related to the others?
a.
intron
b.
tRNA
c.
polypeptide
d.
anticodon
 

31. 

During translation, the type of amino acid that is added to the growing polypeptide depends on the
a.
codon on the mRNA only.
b.
anticodon on the mRNA only.
c.
anticodon on the tRNA to which the amino acid is attached only.
d.
codon on the mRNA and the anticodon on the tRNA to which the amino acid is attached.
 

32. 

Genes contain instructions for assembling
a.
purines.
b.
nucleosomes.
c.
proteins.
d.
pyrimidines.
 

33. 

Which of the following statements is false?
a.
Some genes code for enzymes.
b.
The instructions for making some proteins are not specified by genes.
c.
An organism’s inherited traits depend on proteins.
d.
An organism’s genes determine its inherited traits.
 

34. 

Which of the following is NOT a gene mutation?
a.
inversion
b.
insertion
c.
deletion
d.
substitution
 

35. 

Which of the following is NEVER a frameshift mutation?
a.
substitution
b.
insertion
c.
deletion
d.
point mutation
 

36. 

A promoter is a
a.
binding site for DNA polymerase.
b.
binding site for RNA polymerase.
c.
start signal for transcription.
d.
stop signal for transcription.
 

37. 

If a specific kind of protein is not continually used by a cell, the gene for that protein is
a.
always transcribed.
b.
never expressed.
c.
turned on and off at different times.
d.
not regulated.
 

38. 

Which of the following is NOT generally part of a eukaryotic gene?
a.
operon
b.
TATA box
c.
promoter sequences
d.
enhancer sequences
 

39. 

Which of the following statements is false?
a.
Mutations do not occur in hox genes.
b.
Hox genes that are found in different animals are very different from each other.
c.
Hox genes control the normal development of an animal.
d.
Hox genes occur in clusters.
 

40. 

Hox genes
a.
are regulated by operons.
b.
are found in bacteria.
c.
are not found in humans.
d.
determine the location of a dog’s ears.
 



 
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